Enhancing Performance in Pre-Filled Syringe Inspection: Antares Vision Group's Advanced Solutions

Pre-filled syringes (PFS) are increasingly favored in the pharmaceutical industry, particularly for biologic formulations and ophthalmic injections that require precise, low-volume dosing. They offer significant advantages, including reduced risk of contamination, suitability for patient self-delivery, and efficient use of expensive drug products due to minimal overfill requirements. However, PFS presents unique challenges in filling, sealing, inspecting, and conducting specific tests for primary packaging integrity.

Inspection for visible particulates and other quality control measures are crucial to meet these stringent requirements. Every dosage unit intended for parenteral administration must be thoroughly inspected to ensure it is essentially free of particle contamination. Moreover, functionality tests are necessary to verify the proper movement of the plunger within the syringe barrel and ensure the highest quality and safety standards are met.

Given these challenges, Antares Vision Group offers two state-of-the-art solutions for the automatic visual inspection of pre-filled syringes:

VRI VI for Pre-Filled Syringes

The VRI VI solution is designed for high-speed, high-performance inspection of glass and plastic pre-filled syringes, handling up to 400 pieces per minute. This advanced system integrates Automatic Visual Inspection (AVI) with Container Closure Integrity Testing (CCIT) using high-voltage technology. It can inspect the entire surface of each syringe, ensuring comprehensive quality control.

Key Features:

• Processing Speed: Up to 400 pcs/min
• Product Content: Suitable for various liquids, including water-like, oily (not in case of CCIT), suspension and emulsion
• Advanced Detection: Capable of identifying particles such as reflecting and non-reflecting fibers, floating and heavy particles
• Add-ons: Leak Detection, Digital Factory modules for enhanced productivity, AI integration for inspection and predictive maintenance, code verification, OCR-OCV, and serialization

CY Convel Tech

For slightly smaller-scale operations, the CY Convel Tech offers reliable inspection of pre-filled syringes at speeds up to 200 pieces per minute. This solution combines Automatic Visual Inspection with high-voltage leak detection, featuring patented technology that excels in identifying microcracks or pinholes in syringe containers, ensuring sterility and safety.

Key Features:

• Processing Speed: Up to 200 pcs/min
• Compact and Reliable Design: Optimized for various operational environments
• Comprehensive Inspection: Detects particles and checks for cosmetic defects, ensuring product integrity
• High Voltage Leak Detection: Ensures the highest level of sterility by detecting even the smallest container defects

Comparing VRI VI and CY Convel Tech: Which Solution Fits Your Needs?

When choosing between the VRI VI and the CY Convel Tech, it’s important to consider the specific requirements of your production line:

• Speed and Throughput: The VRI VI is ideal for high-volume production environments, with the capability to process up to 400 pcs/min, making it suitable for large-scale operations. On the other hand, the CY Convel Tech, with its processing speed of up to 200 pcs/min, is better suited for smaller-scale or more specialized production lines.
• Container Compatibility: Both systems are designed to handle glass and plastic pre-filled syringes, but the VRI VI offers more flexibility in handling a wider range of liquid types, including suspensions and emulsions, beyond just water-like liquids.
• Inspection Capabilities: The VRI VI’s additional features, such as the Digital Factory modules and AI integration, enhance inspection accuracy and operational efficiency, making it a more comprehensive solution for complex inspection needs.
• Design and Integration: The CY Convel Tech’s compact and reliable design makes it easier to integrate into existing lines where space might be limited. It also offers specialized high-voltage leak detection, which is crucial for maintaining sterility in pre-filled syringes.

Conclusion

Antares Vision Group’s comprehensive approach to pre-filled syringe inspection addresses the pharmaceutical market's diverse and demanding needs. Whether you require the VRI VI's high-speed, advanced capabilities or the CY Convel Tech's reliable, space-efficient design, both solutions ensure that your products meet the highest standards of quality and safety.